Finding a Place for Tumor-specific T Cells in Targeted Cancer Therapy
نویسنده
چکیده
A goal in cancer therapeutics is to develop targeted modalities that distinguish malignant from normal cells. T cells can discriminate diseased cells based on subtle alterations in peptides displayed in association with MHC molecules at the cell surface. Recent success using the adoptive transfer of tumor-specific T cells has fueled optimism that this approach may find a place as a targeted therapy for some human cancers.
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 200 شماره
صفحات -
تاریخ انتشار 2004